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Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion

Alternative mRNA splicing is a mechanism to regulate protein isoform expression and is regulated by alternative splicing factors. The alternative splicing factor 45 (SPF45) is overexpressed in cancer, although few biological effects of SPF45 are known, and few splicing targets have been identified....

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Hlavní autoři: Liu, Yuying, Conaway, LaShardai, Rutherford Bethard, Jennifer, Al-Ayoubi, Adnan M., Thompson Bradley, Amber, Zheng, Hui, Weed, Scott A., Eblen, Scott T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643583/
https://ncbi.nlm.nih.gov/pubmed/23519612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt170
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