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In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity.

Pirodavir (R 77975) is the prototype of a novel class of broad-spectrum antipicornavirus compounds. Although its predecessor, R 61837, a substituted phenyl-pyridazinamine, was effective in inhibiting 80% of 100 serotypes tested (EC80) at concentrations above 32 micrograms/ml, pirodavir inhibits the...

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Bibliografische gegevens
Hoofdauteurs: Andries, K, Dewindt, B, Snoeks, J, Willebrords, R, van Eemeren, K, Stokbroekx, R, Janssen, P A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189235/
https://ncbi.nlm.nih.gov/pubmed/1317142
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