CC12, A High Affinity Ligand for (3)H-Cimetidine Binding, is an Improgan Antagonist

Improgan, a chemical congener of cimetidine, is a highly effective non-opioid analgesic when injected into the CNS. Despite extensive characterization, neither the improgan receptor, nor a pharmacological antagonist of improgan has been previously described. Presently, the specific binding of (3)H-c...

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Detalhes bibliográficos
Main Authors: Hough, Lindsay B., Nalwalk, Julia W., Phillips, James G., Kern, Brian, Shan, Zhixing, Wentland, Mark P., de Esch, Iwan J.P., Janssen, Elwin, Barr, Travis, Stadel, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892205/
https://ncbi.nlm.nih.gov/pubmed/17336343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.01.004
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