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Effect of protein binding in serum on therapeutic efficacy of cephem antibiotics.

The effect of protein binding in serum of eight cephem antibiotics (ceftazidime, ceftizoxime, cefotiam, cefmetazole, cefpiramide, cefazolin, cefuzonam, ceftriaxone) on their therapeutic efficacies was examined in mice with experimentally induced intraperitoneal infections or pneumonia. The relations...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Tawara, S, Matsumoto, S, Kamimura, T, Goto, S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189219/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1590685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.1.17
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