Effect of protein binding in serum on therapeutic efficacy of cephem antibiotics.

The effect of protein binding in serum of eight cephem antibiotics (ceftazidime, ceftizoxime, cefotiam, cefmetazole, cefpiramide, cefazolin, cefuzonam, ceftriaxone) on their therapeutic efficacies was examined in mice with experimentally induced intraperitoneal infections or pneumonia. The relations...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Tawara, S, Matsumoto, S, Kamimura, T, Goto, S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1590685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.1.17
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