Phosphoinositide-Dependent Pathways in Mouse Sperm are Regulated by Egg ZP3 and Drive the Acrosome Reaction

Sperm of many animals must complete an exocytotic event, the acrosome reaction, in order to fuse with eggs. In mammals, acrosome reactions are triggered during sperm contact with the egg extracellular matrix, or zona pellucida, by the matrix glycoprotein ZP3. Here, we show that ZP3 stimulates produc...

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Bibliografiske detaljer
Main Authors: Jungnickel, Melissa K., Sutton, Keith A., Wang, Yanli, Florman, Harvey M.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892180/
https://ncbi.nlm.nih.gov/pubmed/17258189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.12.023
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