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Ca(2+) Entry through Store-operated Channels in Mouse Sperm Is Initiated by Egg ZP3 and Drives the Acrosome Reaction

Fertilization occurs after the completion of the sperm acrosome reaction, a secretory event that is triggered during gamete adhesion. ZP3, an egg zona pellucida glycoprotein, produces a sustained increase of the internal Ca(2+) concentration in mouse sperm, leading to acrosome reactions. Here we sho...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: O'Toole, Christine M.B., Arnoult, Christophe, Darszon, Alberto, Steinhardt, Richard A., Florman, Harvey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10793136/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.5.1571
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