Ca(2+) Entry through Store-operated Channels in Mouse Sperm Is Initiated by Egg ZP3 and Drives the Acrosome Reaction

Fertilization occurs after the completion of the sperm acrosome reaction, a secretory event that is triggered during gamete adhesion. ZP3, an egg zona pellucida glycoprotein, produces a sustained increase of the internal Ca(2+) concentration in mouse sperm, leading to acrosome reactions. Here we sho...

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Bibliografiske detaljer
Main Authors: O'Toole, Christine M.B., Arnoult, Christophe, Darszon, Alberto, Steinhardt, Richard A., Florman, Harvey M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2000
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14868/
https://ncbi.nlm.nih.gov/pubmed/10793136
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