TRAIL-Mediated Apoptosis in HIV-1-Infected Macrophages Is Dependent on the Inhibition of Akt-1 Phosphorylation

HIV-1 uses mononuclear phagocytes (monocytes, tissue macrophages, and dendritic cells) as a vehicle for its own dissemination and as a reservoir for continuous viral replication. The mechanism by which the host immune system clears HIV-1-infected macrophages is not understood. TRAIL may play a role...

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Hlavní autoři: Huang, Yunlong, Erdmann, Nathan, Peng, Hui, Herek, Shelley, Davis, John S., Luo, Xu, Ikezu, Tsuneya, Zheng, Jialin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892167/
https://ncbi.nlm.nih.gov/pubmed/16887991
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