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Functional interaction between c-Abl and the p21-activated protein kinase γ-PAK

A member of the p21-activated protein kinase (PAK) family, γ-PAK has cytostatic properties and is activated by cellular stresses such as hyperosmolarity or DNA damage. We report herein that γ-PAK is associated in vivo with the nonreceptor protein tyrosine kinase c-Abl. γ-PAK phosphorylates c-Abl on...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Roig, Joan, Tuazon, Polygena T., Zipfel, Patricia A., Pendergast, Ann Marie, Traugh, Jolinda A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11121037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.26.14346
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