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Modeling of phosphomethyl pyrimidine kinase from Leptospira interrogans serovar lai strain 56601

Many microorganisms, as well as plants and fungi, synthesize thiamin, but vertebrates do not produce it. Phosphomethyl pyrimidine kinase is an enzyme involved in an intermediary step of thiamin biosynthesis from purine molecules. This enzyme is absent in humans. Thus, it is a potential chemotherapeu...

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Hlavní autoři: Umashankar, Vetrivel, Subramanian, Gurunathan, Dorairaj, Sudarsanam
Médium: Artigo
Jazyk:Inglês
Vydáno: Biomedical Informatics Publishing Group 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891682/
https://ncbi.nlm.nih.gov/pubmed/17597880
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