Isoleucine Biosynthesis in Leptospira interrogans Serotype lai Strain 56601 Proceeds via a Threonine-Independent Pathway

Three leuA-like protein-coding sequences were identified in Leptospira interrogans. One of these, the cimA gene, was shown to encode citramalate synthase (EC 4.1.3.-). The other two encoded α-isopropylmalate synthase (EC 4.1.3.12). Expressed in Escherichia coli, the citramalate synthase was purified...

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Detalhes bibliográficos
Main Authors: Xu, Hai, Zhang, Yuzhen, Guo, Xiaokui, Ren, Shuangxi, Staempfli, Andreas A., Chiao, Juishen, Jiang, Weihong, Zhao, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Physiology and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC490871/
https://ncbi.nlm.nih.gov/pubmed/15292141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.16.5400-5409.2004
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