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Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance.

In this study, we examined the mechanism of translation of the human immunodeficiency virus type 1 tat mRNA in eucaryotic cells. This mRNA contains the tat open reading frame (ORF), followed by rev and nef ORFs, but only the first ORF, encoding tat, is efficiently translated. Introduction of prematu...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Luukkonen, B G, Tan, W, Schwartz, S
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769666/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4086-4094.1995
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