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Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance.

In this study, we examined the mechanism of translation of the human immunodeficiency virus type 1 tat mRNA in eucaryotic cells. This mRNA contains the tat open reading frame (ORF), followed by rev and nef ORFs, but only the first ORF, encoding tat, is efficiently translated. Introduction of prematu...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Luukkonen, B G, Tan, W, Schwartz, S
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769666/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4086-4094.1995
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