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Serum Differentially Alters the Antifungal Properties of Echinocandin Drugs

Antifungal efficacies of the echinocandin drugs caspofungin, micafungin, and anidulafungin were reduced significantly in the presence of 50% human serum, which yielded nearly equivalent MICs or minimum effective concentrations against diverse Candida spp. and Aspergillus spp. Consistent with a direc...

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Main Authors: Paderu, Padmaja, Garcia-Effron, Guillermo, Balashov, Sergey, Delmas, Guillaume, Park, Steven, Perlin, David S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891414/
https://ncbi.nlm.nih.gov/pubmed/17420211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01536-06
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