The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells.
In susceptible mice, the murine AIDS (MAIDS) defective virus can induce marked expansion of its target cells, the majority of which belong to the B-cell lineage. This expansion, which appears to be critical for the development of the immunodeficiency syndrome, is initially polyclonal but becomes oli...
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| Udgivet i: | J Virol |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4069-4078.1995 |
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