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The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells.

In susceptible mice, the murine AIDS (MAIDS) defective virus can induce marked expansion of its target cells, the majority of which belong to the B-cell lineage. This expansion, which appears to be critical for the development of the immunodeficiency syndrome, is initially polyclonal but becomes oli...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Huang, M, Takac, M, Kozak, C A, Jolicoeur, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769664/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4069-4078.1995
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