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The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells.

In susceptible mice, the murine AIDS (MAIDS) defective virus can induce marked expansion of its target cells, the majority of which belong to the B-cell lineage. This expansion, which appears to be critical for the development of the immunodeficiency syndrome, is initially polyclonal but becomes oli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, M, Takac, M, Kozak, C A, Jolicoeur, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189141/
https://ncbi.nlm.nih.gov/pubmed/7769664
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