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Effects of Piperaquine, Chloroquine, and Amodiaquine on Drug Uptake and of These in Combination with Dihydroartemisinin against Drug-Sensitive and -Resistant Plasmodium falciparum Strains

Piperaquine is being developed as a long-acting component in artemisinin combination therapies. It was highly active in vitro and drug interaction studies showed that dihydroartemisinin combinations with piperaquine, chloroquine, and amodiaquine were indifferent tending toward antagonism. Competitiv...

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Detalhes bibliográficos
Main Authors: Fivelman, Quinton L., Adagu, Ipemida S., Warhurst, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891407/
https://ncbi.nlm.nih.gov/pubmed/17404003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01479-06
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