Sensitivity of Monkey B Virus (Cercopithecine herpesvirus 1) to Antiviral Drugs: Role of Thymidine Kinase in Antiviral Activities of Substrate Analogs and Acyclonucleosides

Herpes B virus (B virus [BV]) is a macaque herpesvirus that is occasionally transmitted to humans where it can cause rapidly ascending encephalitis that is often fatal. To understand the low susceptibility of BV to the acyclonucleosides, we have cloned, expressed, and characterized the BV thymidine...

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Detalhes bibliográficos
Main Authors: Focher, Federico, Lossani, Andrea, Verri, Annalisa, Spadari, Silvio, Maioli, Andrew, Gambino, Joseph J., Wright, George E., Eberle, Richard, Black, Darla H., Medveczky, Peter, Medveczky, Maria, Shugar, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891389/
https://ncbi.nlm.nih.gov/pubmed/17438061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01284-06
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