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Immunogenicity of the outer domain of a HIV-1 clade C gp120

BACKGROUND: The possibility that a sub domain of a C clade HIV-1 gp120 could act as an effective immunogen was investigated. To do this, the outer domain (OD) of gp120(CN54 )was expressed and characterized in a construct marked by a re-introduced conformational epitope for MAb 2G12. The expressed se...

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Bibliographic Details
Main Authors: Chen, Hongying, Xu, Xiaodong, Jones, Ian M
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891314/
https://ncbi.nlm.nih.gov/pubmed/17509143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-33
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