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Differential homing mechanisms regulate regionalized effector CD8αβ(+) T cell accumulation within the small intestine

The CC chemokine receptor (CCR)9 is expressed on the majority of small intestinal, but few colonic, T cells, whereas its ligand CCL25 is constitutively expressed by small intestinal epithelial cells. As such, CCR9/CCL25 have been proposed to play a central role in regulating small intestinal but not...

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Detalhes bibliográficos
Main Authors: Stenstad, Hanna, Svensson, Marcus, Cucak, Helena, Kotarsky, Knut, Agace, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891238/
https://ncbi.nlm.nih.gov/pubmed/17551016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700269104
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