The complement control protein homolog of herpesvirus saimiri regulates serum complement by inhibiting C3 convertase activity.

The herpesvirus saimiri genome encodes a complement control protein homolog (CCPH). Stable mammalian cell transfectants expressing a recombinant transmembrane form of CCPH (mCCPH) or a 5'FLAG epitope-tagged mCCPH (5'FLAGmCCPH) conferred resistance to complement-mediated cell damage by inhibiting the...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Fodor, W L, Rollins, S A, Bianco-Caron, S, Rother, R P, Guilmette, E R, Burton, W V, Albrecht, J C, Fleckenstein, B, Squinto, S P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7745740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.6.3889-3892.1995
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