The complement control protein homolog of herpesvirus saimiri regulates serum complement by inhibiting C3 convertase activity.

The herpesvirus saimiri genome encodes a complement control protein homolog (CCPH). Stable mammalian cell transfectants expressing a recombinant transmembrane form of CCPH (mCCPH) or a 5'FLAG epitope-tagged mCCPH (5'FLAGmCCPH) conferred resistance to complement-mediated cell damage by inhi...

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Autores principales: Fodor, W L, Rollins, S A, Bianco-Caron, S, Rother, R P, Guilmette, E R, Burton, W V, Albrecht, J C, Fleckenstein, B, Squinto, S P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC189111/
https://ncbi.nlm.nih.gov/pubmed/7745740
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