Cardiac autophagy is a maladaptive response to hemodynamic stress

Cardiac hypertrophy is a major predictor of heart failure and a prevalent disorder with high mortality. Little is known, however, regarding mechanisms governing the transition from stable cardiac hypertrophy to decompensated heart failure. Here, we tested the role of autophagy, a conserved pathway m...

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Hlavní autoři: Zhu, Hongxin, Tannous, Paul, Johnstone, Janet L., Kong, Yongli, Shelton, John M., Richardson, James A., Le, Vien, Levine, Beth, Rothermel, Beverly A., Hill, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890995/
https://ncbi.nlm.nih.gov/pubmed/17607355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27523
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