Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3

BACKGROUND: The endothelial cell protein C receptor (EPCR) presents protein C to the thrombin:thrombomodulin complex on the endothelium of large vessels, and enhances the generation of activated protein C (APC) and activation of protease-activated receptor-1. A previous report has demonstrated bindi...

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Autores principales: VILLEGAS-MENDEZ, A, MONTES, R, AMBROSE, L R, WARRENS, A N, LAFFAN, M, LANE, D A
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2007
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890847/
https://ncbi.nlm.nih.gov/pubmed/17459006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2007.02480.x
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