Roles of RabGEF1/Rabex-5 domains in regulating FcϵRI surface expression and FcϵRI-dependent responses in mast cells

RabGEF1/Rabex-5, a guanine nucleotide exchange factor (GEF) for the endocytic pathway regulator, Rab5, contains a Vps9 domain, an A20-like zinc finger (ZnF) domain, and a coiled coil domain. To investigate the importance of these domains in regulating receptor internalization and cell activation, we...

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Detalhes bibliográficos
Main Authors: Kalesnikoff, Janet, Rios, Eon J., Chen, Ching-Cheng, Alejandro Barbieri, M., Tsai, Mindy, Tam, See-Ying, Galli, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890836/
https://ncbi.nlm.nih.gov/pubmed/17341663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-067363
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