Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.

Overcoming hepatitis B virus infection essentially depends on the appropriate immune response of the infected host. Among the hepatitis B virus antigens, the core (HBcAg) and e (HBeAg) proteins appear highly immunogenic and induce important lymphocyte effector functions. In order to investigate the...

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Pubblicato in:	J Virol
Autori principali:	Jung, M C, Diepolder, H M, Spengler, U, Wierenga, E A, Zachoval, R, Hoffmann, R M, Eichenlaub, D, Frösner, G, Will, H, Pape, G R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7538172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.6.3358-3368.1995
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