Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.

Overcoming hepatitis B virus infection essentially depends on the appropriate immune response of the infected host. Among the hepatitis B virus antigens, the core (HBcAg) and e (HBeAg) proteins appear highly immunogenic and induce important lymphocyte effector functions. In order to investigate the...

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Detalhes bibliográficos
Main Authors: Jung, M C, Diepolder, H M, Spengler, U, Wierenga, E A, Zachoval, R, Hoffmann, R M, Eichenlaub, D, Frösner, G, Will, H, Pape, G R
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189048/
https://ncbi.nlm.nih.gov/pubmed/7538172
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