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pH dependence and inhibition by extracellular calcium of proton currents via plasmalemmal vacuolar-type H(+)-ATPase in murine osteoclasts

The vacuolar-type H(+)-ATPase (V-ATPase) in the plasma membrane of a variety of cells serves as an acid-secreting pathway, and its activity is closely related to cellular functions. Massive proton secretion often leads to electrolyte disturbances in the vicinity of the cell and may in turn affect th...

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Main Authors: Sakai, Hiromu, Kawawaki, Junko, Moriura, Yoshie, Mori, Hiroyuki, Morihata, Hirokazu, Kuno, Miyuki
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890368/
https://ncbi.nlm.nih.gov/pubmed/16901940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.117176
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