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pH dependence and inhibition by extracellular calcium of proton currents via plasmalemmal vacuolar-type H(+)-ATPase in murine osteoclasts

The vacuolar-type H(+)-ATPase (V-ATPase) in the plasma membrane of a variety of cells serves as an acid-secreting pathway, and its activity is closely related to cellular functions. Massive proton secretion often leads to electrolyte disturbances in the vicinity of the cell and may in turn affect th...

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Autori principali: Sakai, Hiromu, Kawawaki, Junko, Moriura, Yoshie, Mori, Hiroyuki, Morihata, Hirokazu, Kuno, Miyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890368/
https://ncbi.nlm.nih.gov/pubmed/16901940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.117176
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