Rapid evolution of cancer/testis genes on the X chromosome

BACKGROUND: Cancer/testis (CT) genes are normally expressed only in germ cells, but can be activated in the cancer state. This unusual property, together with the finding that many CT proteins elicit an antigenic response in cancer patients, has established a role for this class of genes as targets...

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Dettagli Bibliografici
Autori principali: Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, Simpson, Andrew J, Jongeneel, C Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890293/
https://ncbi.nlm.nih.gov/pubmed/17521433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-129
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