Rapid evolution of cancer/testis genes on the X chromosome

BACKGROUND: Cancer/testis (CT) genes are normally expressed only in germ cells, but can be activated in the cancer state. This unusual property, together with the finding that many CT proteins elicit an antigenic response in cancer patients, has established a role for this class of genes as targets...

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Bibliografske podrobnosti
Main Authors: Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, Simpson, Andrew J, Jongeneel, C Victor
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890293/
https://ncbi.nlm.nih.gov/pubmed/17521433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-129
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