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Herpes simplex virus type 1 DNA replication is specifically required for high-frequency homologous recombination between repeated sequences.

Using an assay for recombination that measures deletion of a beta-galactosidase gene positioned between two directly repeated 350-bp sequences in plasmids transiently maintained in COS cells, we have found that replication from a simian virus 40 origin produces a high frequency of nonhomologous reco...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Dutch, R E, Bianchi, V, Lehman, I R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3084-3089.1995
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