Herpes simplex virus type 1 DNA replication is specifically required for high-frequency homologous recombination between repeated sequences.
Using an assay for recombination that measures deletion of a beta-galactosidase gene positioned between two directly repeated 350-bp sequences in plasmids transiently maintained in COS cells, we have found that replication from a simian virus 40 origin produces a high frequency of nonhomologous reco...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707536/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3084-3089.1995 |
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