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Replication in vitro and in vivo of an equine infectious anemia virus mutant deficient in dUTPase activity.

As an important enzyme in DNA synthesis, dUTPase is present in a wide variety of organisms and viruses and has been identified as a component of the equine infectious anemia virus (EIAV) pol gene. The role of EIAV dUTPase, designated DU, in virus replication in vitro and in vivo was investigated wit...

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Publicat a:J Virol
Autors principals: Lichtenstein, D L, Rushlow, K E, Cook, R F, Raabe, M L, Swardson, C J, Kociba, G J, Issel, C J, Montelaro, R C
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707512/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.2881-2888.1995
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