Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules.

Antiviral cytotoxic T lymphocytes (CTL) may play a role in clearance of hepatitis C virus (HCV)-infected cells and thereby cause hepatocellular injury during acute and chronic HCV infection. The aim of this study was to identify HLA-A2.1-restricted HCV T-cell epitopes and to evaluate whether anti-HC...

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Detalhes bibliográficos
Main Authors: Battegay, M, Fikes, J, Di Bisceglie, A M, Wentworth, P A, Sette, A, Celis, E, Ching, W M, Grakoui, A, Rice, C M, Kurokohchi, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188921/
https://ncbi.nlm.nih.gov/pubmed/7884894
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