Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor.

Development of viral resistance to the aminodiol human immunodeficiency virus (HIV) protease inhibitor BMS 186,318 was studied by serial passage of HIV type 1 RF in MT-2 cells in the presence of increasing concentrations of compound. After 11 passages, an HIV variant that showed a 15-fold increase i...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Patick, A K, Rose, R, Greytok, J, Bechtold, C M, Hermsmeier, M A, Chen, P T, Barrish, J C, Zahler, R, Colonno, R J, Lin, P F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188882/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2148-2152.1995
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