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Dectin-1 is required for β-glucan recognition and control of fungal infection
β-Glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear. Here we show that deficiency of dectin-1, the myeloid receptor for β-glucan, rendered mice susceptible to infection with Candida albicans. Dectin-1-deficient leukocytes dem...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1888731/ https://ncbi.nlm.nih.gov/pubmed/17159984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1408 |
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