Peripheral blood mononuclear cells produce normal amounts of defective Vif- human immunodeficiency virus type 1 particles which are restricted for the preretrotranscription steps.

Previous studies have demonstrated the absence of viral replication of Vif- mutants in stimulated primary blood mononuclear cells (PBMC). Human immunodeficiency virus type 1 strain NDK Vif- mutants were propagated on the semipermissive CEM cell line, and the viral stock obtained was compared with th...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Courcoul, M, Patience, C, Rey, F, Blanc, D, Harmache, A, Sire, J, Vigne, R, Spire, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2068-2074.1995
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