Peripheral blood mononuclear cells produce normal amounts of defective Vif- human immunodeficiency virus type 1 particles which are restricted for the preretrotranscription steps.

Previous studies have demonstrated the absence of viral replication of Vif- mutants in stimulated primary blood mononuclear cells (PBMC). Human immunodeficiency virus type 1 strain NDK Vif- mutants were propagated on the semipermissive CEM cell line, and the viral stock obtained was compared with th...

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Detalhes bibliográficos
Main Authors: Courcoul, M, Patience, C, Rey, F, Blanc, D, Harmache, A, Sire, J, Vigne, R, Spire, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188872/
https://ncbi.nlm.nih.gov/pubmed/7884852
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