Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing

BACKGROUND: Previous studies of individual genes have shown that in a self-enforcing way, dimethylation at histone 3 lysine 9 (dimethyl-H3K9) and DNA methylation cooperate to maintain a repressive mode of inactive genes. Less clear is whether this cooperation is generalized in mammalian genomes, suc...

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Main Authors: Wu, Jiejun, Wang, Shu-Huei, Potter, Dustin, Liu, Joseph C, Smith, Laura T, Wu, Yue-Zhong, Huang, Tim H-M, Plass, Christoph
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888705/
https://ncbi.nlm.nih.gov/pubmed/17524140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-131
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