Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc(+/min) mice

Anti-VEGF-A monoclonal antibodies, in combination with chemotherapy, result in a survival benefit in patients with metastatic colorectal and non-small cell lung cancer, but little is known regarding the impact of anti-VEGF-A therapy on benign or premalignant tumors. The Apc(+/min) mice have been wid...

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Detalhes bibliográficos
Main Authors: Korsisaari, Nina, Kasman, Ian M., Forrest, William F., Pal, Navneet, Bai, Wei, Fuh, Germaine, Peale, Franklin V., Smits, Ron, Ferrara, Napoleone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888576/
https://ncbi.nlm.nih.gov/pubmed/17553957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704213104
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