Biochemical characterization of the metallo-beta-lactamase CcrA from Bacteroides fragilis TAL3636.

The CcrA beta-lactamase from Bacteroides fragilis TAL3636 was cloned into Escherichia coli and purified from inclusion bodies. This group 3 metalloenzyme hydrolyzed most beta-lactam antibiotics, including cephamycins and carbapenems. Following inhibition by chelators, enzyme activity was recovered w...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Yang, Y, Rasmussen, B A, Bush, K
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.1155
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