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Biochemical characterization of the metallo-beta-lactamase CcrA from Bacteroides fragilis TAL3636.

The CcrA beta-lactamase from Bacteroides fragilis TAL3636 was cloned into Escherichia coli and purified from inclusion bodies. This group 3 metalloenzyme hydrolyzed most beta-lactam antibiotics, including cephamycins and carbapenems. Following inhibition by chelators, enzyme activity was recovered w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Y, Rasmussen, B A, Bush, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC188856/
https://ncbi.nlm.nih.gov/pubmed/1510410
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