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ATP-dependent structural change of the eukaryotic clamp-loader protein, replication factor C
The eukaryotic DNA sliding clamp that keeps DNA polymerase engaged at a replication fork, called proliferating cell nuclear antigen (PCNA), is loaded onto the 3′ ends of primer DNA through its interaction with a heteropentameric protein complex called replication factor C (RFC). The ATPase activity...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC18882/ https://ncbi.nlm.nih.gov/pubmed/11121020 |
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