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Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro.

Inhibition of cytochrome P450IA2 activity is an important adverse effect of quinolone antibacterial agents. It results in a prolonged half-life for some drugs that are coadministered with quinolones, such as theophylline. The objective of the study described here was to define the parameters for qua...

詳細記述

保存先:
書誌詳細
主要な著者: Fuhr, U, Anders, E M, Mahr, G, Sörgel, F, Staib, A H
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC188773/
https://ncbi.nlm.nih.gov/pubmed/1510417
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