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Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro.

Inhibition of cytochrome P450IA2 activity is an important adverse effect of quinolone antibacterial agents. It results in a prolonged half-life for some drugs that are coadministered with quinolones, such as theophylline. The objective of the study described here was to define the parameters for qua...

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Detalhes bibliográficos
Main Authors: Fuhr, U, Anders, E M, Mahr, G, Sörgel, F, Staib, A H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188773/
https://ncbi.nlm.nih.gov/pubmed/1510417
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