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Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment

The Fc receptor-like protein 5 (FCRL5) on B cells has both an immunoreceptor tyrosine-based activation motif (ITAM)-like sequence and two consensus immunoreceptor tyrosine-based inhibitory motifs (ITIM) in its cytoplasmic region. To evaluate its signaling potential, we expressed constructs for chime...

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Hlavní autoři: Haga, Christopher L., Ehrhardt, Götz R. A., Boohaker, Rebecca J., Davis, Randall S., Cooper, Max D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887609/
https://ncbi.nlm.nih.gov/pubmed/17522256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703354104
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