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Use of a human immunodeficiency virus type 1 Rev mutant without nucleolar dysfunction as a candidate for potential AIDS therapy.

Applications of transdominant mutants of human immunodeficiency virus type 1 (HIV-1) regulatory proteins, especially Rev mutant, have been attempted for gene therapy against AIDS, because the Rev protein is essential for viral replication. We have previously reported that a mutant Rev protein (dRev)...

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Detalhes bibliográficos
Main Authors: Furuta, R A, Kubota, S, Maki, M, Miyazaki, Y, Hattori, T, Hatanaka, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188754/
https://ncbi.nlm.nih.gov/pubmed/7853493
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