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HIV-1 nucleic acids localize to the spermatogonia and their progeny. A study by polymerase chain reaction in situ hybridization.

The purpose of this study was to determine the histological distribution of in situ polymerase chain reaction (PCR)-amplified HIV-1 nucleic acids in the male genital tract to elucidate the mechanism of sexual transmission of AIDS. Viral DNA was detected in the testicular tissue of 11 of 12 men with...

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Bibliographic Details
Main Authors: Nuovo, G. J., Becker, J., Simsir, A., Margiotta, M., Khalife, G., Shevchuk, M.
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887452/
https://ncbi.nlm.nih.gov/pubmed/8203455
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